Abstract #16 Debald

Breast cancer is a heterogeneous disease that can be characterized by different patterns of histology, receptor status as well as gene and molecular classifications. All these factors influence the therapy, the prognosis and the outcome for each individual patient. Triple-negative breast cancer (TNBC) is a certain subgroup of breast cancer that is negative for hormone receptors (ER and PR) and lacks overexpression of the Her2/neu protein. This subgroup accounts for 15-20% of all breast cancer cases. Due to its aggressive behavior, the increased risk for metastases and the lack of targeted therapies TNBC has gained major interest in recent years.